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Technology Description

The invention relates to new combinations of boron compounds and adjuvants for use in method to induce myotube formation and suppress cell mortality in a mammal in need thereof and compositions thereof.
This innovative technology helps to minimize the physiological effect of defective mRNA to provide a quality of life for patients with rare disease, as muscular dysthropies, as well as minimizing and reducing the dosages of the suitable boron compounds to non-toxic dosages, to ensure effectivity while reducing or eliminating side effects.

Potential Benefits

This innovative technology comprises new combinations of boron compounds and adjuvants and compositions thereof, suitable for use in a method to induce myotube formation and suppress cell mortality in a mammal in need thereof.
Furthermore, it is related to compositions comprising boron compounds, adjuvants and support platforms, which enhance the effect of synergistic activation of the boron cell membrane transporter (NaBC1) and adhesion receptors in cells.
The invention also refers to the aforementioned combinations and compositions for the treatment of pathophysiological condition, which affects skeletal muscle, such as dystrophy.

Limitations

To be determined during further development.

Suggested Applications

Muscle regeneration
Muscular dystrophy

Case manager

Aida Castellanos Paez

Status
PCT Application
Availability
Licensing or Assignment
Inventor(s)
Patricia Rico, Rafael Castillo, Ana Rodriguez

Centro de Investigación Biomédica en Red, Bioingeniería, Biomateriales y Nanomedicina

Discover the institution >>
The Biomedical Networking Research Center of Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN) is one of the 11 thematic areas of CIBER. CIBER groups some of the main Spanish research groups (more than 400) in biomedicine, located in more than 100 institutions distributed around Spain. Website: http://www.ciber-bbn.es/
The technological areas
Life sciences

Technology Readiness Level 3

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