Technology Description
Spirooxindoles are widely found in bioactive molecules and their synthetic intermediates.
This technology provides a facile method to stereo-selectively synthesize novel spirooxindole derivatives from easily accessible starting materials under mild conditions. These novel spirooxindole derivatives are useful for searching for and developing bioactive/bio-functional molecules.
Potential Benefits
- Synthesis of novel oxa-spirooxindole derivatives
- Asymmetric synthesis of spirooxindole derivatives with functional groups
- Transformation of the synthesized spirooxindole derivatives can further provide new products
Limitations
N.A.
Suggested Applications
Pharmaceutical compound synthons
Diagnostic compounds
Probe molecules for investigating bio-functions
Related materials
figure 0023-0620.75 KB
Status
Patented in multiple jurisdictions
Availability
Licensing
Inventor(s)
Chemistry and Chemical Bioengineering Unit
